Juliana Maria Ulfah, Noni Novisari Soeroso, Pantas Hasibuan, Putri Chairani Eyanoer
Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Sumatera Utara, RSUP H. Adam Malik Medan.
Epi Treat Unit Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Sumatera Utara.
Background: Atropine is widely used as premedication for fiberoptic bronchoscopy. The anticholinergic action of atropine may reduce tracheobronchial secretions to improve visualization of the tracheobronchial tree, prevent bronchoconstriction and vasovagal reflex. This study were to describe characteristic of patients and to compare premedication with and without atropine in reducing tracheobronchial secretion during bronchoscopy procedure in Adam Malik general hospital.
Methods: In this quasi-experimental study were 60 eligible inpatients who performed bronchoscopy in the installation space of diagnostic integrated department of Adam Malik Hospital Medan from April to June 2014 with a sample of 60 people, consisting of 30 people received premedication atropine, and 30 people received injections of saline solution physiological 1 ml intramuscular as placebo. The sample is determined by consecutive sampling that meet the inclusion and exclusion criteria.
Results: Most of patients were among 40-59 years old (55%), male (81.67%), ex-smoker (80.0%). Grading of tracheobronchial secretions detected as grade 1: no patient with atropine, 2 patients (6.67%) without atropine; grade 2: 27 patients (90.00%) with atropine, 23 patients (76.67%) without atropine; and grade 3: 3 patients (10.00%) with atropine, 5 patients (16.67%) without atropine. Statistically, there was no significant difference in reducing tracheobronchial secretion between premedication with and without atropine (p=1.000, Kolmogorov-Smirnov test).
Conclusions: Atropine premedication prior to bronchoscopy did not affect tracheobronchial secretion during bronchoscopy. (J Respir Indo. 2015; 35: 230-4)
Keywords: Atropine, premedication, fibreoptic bronchoscopy, tracheobronchial secretion.