Category archives for Asthma

Relation Between Interleukin-17 Level in Sputum Induction with FEF25-75% in Asthma

Salva Badjarad, Daniel Maranatha Departemen Pulmonologi dan Kedokteran Respirasi Fakultas Kedokteran Universitas Airlangga, RSUD Dr. Soetomo, Surabaya Abstract Background: Asthma is a chronic obstructive airway disease markedly by inflammation and airway hyperresponsiveness. Astma is one of causes of morbidity and mortality in Indonesia. Asthma has different manifestations of inflammatory patterns such as Th1, Th2 and […]

Ultraviolet Rays Exposure on Levels of Interleukin 17 in Controlled Partial Asthma Patients

Abdulloh Najich, Arief Bakhtiar, Muhammad Amin Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Airlangga, RSUD Dr. Soetomo, Surabaya Abstract Background: Asthma is a serious public health problem in the world, its prevalence is increasing in areas away from the equator, the effect of exposure to ultraviolet (UV) from the sun as protection of allergies. […]

The Role of T-Helper 17 Cells in Asthma

Arry Setyowati, Jatu Aphridasari Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Sebelas Maret, RSUD Dr. Moewardi, Surakarta Abstract Asthma is a worldwide health problem with increasing prevalence in several countries. Inflammatory disorders of chronic breath channel on asthma involves a lot of cells and cellular elements. Inflammatory tract in asthma is triggered by response […]

The Role of Xanthine in Pulmonary Obstructive Disease

Budi Yanti,1 Menaldi Rasmin2 1SMF Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Syiah Kuala, RSUD Dr. Zainoel Abidin, Banda Aceh 2 Departemen Pulmonologi dan Kedokteran Respirasi Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta Abstract Theophylline has been used in the treatment of asthma and chronic obstructive pulmonary disease (COPD) for over 60 years and remains […]

Asthma Medication Adherence and Quality of Life in Persistent Asthma Patients

Rayyan Fitri,1 Herry Priyanto,1 Tristia Rinanda2 1Bagian Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Syiah Kuala 2Bagian Mikrobiologi, Fakultas Kedokteran Universitas Syiah Kuala Abstract Background: Adherence levels of persistent asthma patients to regular medication of asthma is still low, resulting in uncontrolled asthma that cause the clinical consequences such as asthma exacerbations and decreased quality […]

Association Between Vitamin D level with Asthma Control Level

Aulia Rahim, Masrul Basyar,Yessy Susanty Sabri, Sabrina Ermayanti Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Andalas, Padang Abstract Background: Vitamin D has a role as an immunomodulator in asthma. Low vitamin D levels are associated with poor asthma control, reduced lung function, resistence steroid and e acerbation. Little is known about vitamin D in […]

Comparison of Asthma Control Level Among Patients with Asthma in Dust Exposed Area to Unexposed Area of Padang Cement Company

Fadhli Muhammad Kurnia, Irvan Medison, Sabrina Ermayanti, Yessy Susanty Sabri Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Andalas, RSUP Dr. M.Djamil, Padang Abstract Background: The prevalence of asthma increased in industrialized countries. One of the industrialization influence is increasing air pollution, where air pollution is known to affect the level of asthma control. The […]

Effect of Omega 3 in Interleukin-4 Serum Levels and FEV1 of Asthmatic Patients

Navratilova Melfia, Suradi, Sutanto SMF Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Sebelas Maret, RS Dr. Moewardi, Surakarta Abstract Background: Treatment of asthma is to achieve controled asthma. Decline in a proinflamatory asthma cytokine, interleukin-4 (IL-4) serum improve lung function in order to reach the level of asthma control. Omega 3 suppress the secretion of […]

Related Factors of Asthma Control Level in Dr. Soetomo Hospital

Ni Wayan Candrawati, Muhammad Amin Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Airlangga, RSUD Dr. Soetomo, Surabaya Abstract Introduction: Identifying and treating modifiable risk factors associated with asthma control can optimalize asthma control. Factors associated with uncontrolled asthma are age, sex, educational level, smoking, FEV1, co-morbidities and overweight. The aim of study was to […]

Association between Serum Magnesium Level and Degree of Asthma Control

Hendresta, Yessy S Sabri, Masrul Basyar, Oea Khairsyaf Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Andalas Abstract Background: Magnesium has important rule to prevent bronchoconstriction in asthma, effected smooth muscle relaxation. Hypomagnesemia related to bronchial hyperresponsivity that can lead to poor control of asthma. The aim of this study is to determine association between serum […]

Exposure of Wheat Flour Dust Exposure to Occupational Asthma at Bakery Workers PT X in Medan

Desdiani¹, Faisal Yunus², Nuryunita Nainggolan¹, Putri Chairani Eyanoer³ ¹Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Sumatera Utara, RSUP H. Adam Malik Medan ²Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Indonesia, RS Persahabatan, Jakarta ³Lembaga Penelitian Pengembangan Masyarakat Universitas Sumatera Utara Abstract Background: Wheat flour dust can cause occupational asthma of bakery […]

The Risk Factor of Asthma in Elementary Students Medan

Rizky Ramdhani, Noni Novisari Soeroso Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Sumatera Utara, RSUP H. Adam Malik, Medan Abstract Background: Asthma is one of the most chronic inflammatory diseases in the world. The suffer from asthma prevalence is increasing, especially in urban communities and the people who do the urbanization. Methods: This […]

Correlation between Serum Adiponectin with Severity Degree of Asthma

Wa Ode Nelly Estika, Nur Ahmad Tabri, Muhammad Harun Iskandar Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Hasanuddin, Makassar Abstract Background: Adiponectin is a one of adipocytokine that mediate antiinflammation and has a role in asthma. Adiponectin and its receptor (AdipoR1, AdipoR2, T-cadherin) are expressed on multiple cell types in the lung. Correlation between adiponectin […]

Efficacy of 36 mg/day vs 12 mg/day Oral Prednisolone in Treatment of Moderate Persistent Asthma Following Acute Exacerbation

Oke Viska, Faisal Yunus, Wiwien Heru Wiyono Departemen Pulmonologi dan Ilmu Kedokteran Respirasi, Fakultas Kedokteran Universitas Indonesia, RS Persahabatan, Jakarta, Indonesia Abstract Background: Efforts to reduce the recurrence of asthma exacerbations is optimal handling. Steroid has a role in reducing exacerbations, but another problem arises due to uneffective oral dose after the patient is discharged. This study […]

Batik Wax Vapour (Malam) Exposure on Lung Function and Occupational Asthma of Traditional Batik Industry Workers

Eva Lydia Munthe¹, Suradi¹, Eddy Surjanto¹, Faisal Yunus² Departemen Pulmonologi dan Ilmu Kedokteran Respirasi, Fakultas Kedokteran Universitas Sebelas Maret, RSUD dr. Moewardi, Surakarta Departemen Pulmonologi dan Ilmu Kedokteran Respirasi, Fakultas Kedokteran Universitas Indonesia, RS Persahabatan, Jakarta Abstract Background: Batik is a high artistic craft and a part of Indonesian culture especially in Java that using heating wax […]

Impact of Chemical Agent Exposure During Batik Colouring Process to Lung Clinical Impairment of Batik’s Industry Worker

Riana Sari, Suradi, Faisal Yunus Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Sebelas Maret, RSUD Dr. Moewardi, Surakarta Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta Abstract Background: Batik is a craft which has a high art and culture value to Indonesian especially Javanese. Chemical agents exposure at the batik coloring […]

Correlation between Asthma Control Test with FEV1% in Determining Asthma Control Level

Anita Ramlie, Retno Ariza Soeprihatini Soemarwoto, Wiwien Heru Wiyono Klinik Respirasi Harum Melati, Pringsewu, Lampung; Departemen Pulmonologi dan Ilmu Kedokteran Respirasi, Fakultas Kedokteran Universitas Indonesia, RS Persahabatan Jakarta Abstract Background: Asthma is a chronic inflammatory disease, so the appropriate treatment is necessary in order to achieve and maintain asthma control for an extended period. Asthma control […]

Asthma Control Level and The Relation with Morbidity and Risk Factors, A Longitudinal Study in Outpatient Clinic in Persahabatan Hospital

Samsul Afandi, Faisal Yunus, Sita Andarini, Aria Kekalih Abstract Background : Previous studyshowed that there were still a lot of uncontrolled asthma patients in Persahabatan Hospital. This study try to describe the asthma control level in longitudinal design. Methods : Subjects of this study were all persistent asthma patient in Persahabatan Hospital within six month period. All […]

Levels of Exhaled Nitric Oxide in Controlled and Uncontrolled Asthma based on Asthma Control Test in Persahabatan Hospital

Ni Made Restiawati, Faisal Yunus, Ratnawati. Abstract Background : Exhaled nitric oxide (FeNO) is recognized as reliable surrogate marker of eosinophilic airway inflammation in asthma patient and offers the advantage of being completely non-invasive and easy procedure. Methods : This cross-sectional comparative study involves 96 asthmatic subjects which then classified into two main categories : […]

Association Between Vitamin D Level with Asthma Control Level, Lung Function, Interleukin-10 and Interleukin-17 in Persistent Bronchial Asthma Patients

Rina Lestari, Susanthy Djajalaksana, Harun Al Rasyid Abstract Background : Vitamin D deficiency is hypothesized to play a role in increasing incidence of asthma. Vitamin D has a role as an immunomodulator in asthma. Current research on vitamin D and asthma hasn’t been studied in adult asthma in Indonesia. The aim of this study was […]

Allergic Bronchopulmonary Aspergillosis

Jamal Zaini Abstract Allergic bronchopulmonary aspergillorsis (ABPA) is a hypersensitivity disorder induced by a fungus Aspergillus fumigatus in the lung, although the precise mechanism need further exploration, this clinical entity mostly found in difficult asthma or cystic fibrosis with the prevalence around 7-18 % in asthmatics and 5-10% in cystic fibrosis. The diagnosis is based […]

Exhaled Nitric Oxide (FeNO) in Patients with Asthma Exacerbation and in Non Exacerbation at Persahabatan Hospital

Arief Riadi Arifin, Faisal Yunus, Ratnawati, Aria Kekalih Abstract Background : Nitric oxide is detected in expired air which is physiologically released by epithedial cells of pulmonary vasculature, cells of lower respiratory tract, upper respiratory tract and paranasal sinuses. Levels in normal human expiratory air range from 5-10 parts per billion (ppb); which is increased […]

Comparison of the Effect of Nebulization between Salbutamol and Salbutamol Diluted with Normal Saline in Adult Patient with Moderate Asthma Exacerbation in Persahabatan Hospital

Indri Savitri Idrus, Faisal Yunus, Sita Laksmi Andarini, Arini Setiawati Abstract Background: Asthma is a chronic airway disease that causes difficulty in breathing in which bronchospasm is a hallmark in acute exacerbation. In management of asthma attack, agonist β2 is the best option as treatment for mild, moderate and severe asthma. Agonist β2 nebulization as […]

Pathophysiology and Markers of Airway Remodeling in Bronchial Asthma

Widodo R, Djajalaksana S. J Respir Indones. 2012;32(2):110-9. Abstract Asthma is a chronic inflammatory disease characterized by reversible airflow limitation and airway hyperresponsiveness. Persistent inflammation in airway tissues may lead to structural changes known as airway remodeling and consequently airway obstruction that is not fully reversible and progressive loss of lung function over time. In […]

Prevalence of Asthma in a Group of 13 – 14 Years Old Students Using the ISAAC Written Questionnaire and Bronchial Provocation Test in Central Jakarta

Mustafa J, Yunus F, Wiyono WH. J Respir Indones. 2012;32(1):8-16. Abstract Introduction: Prevalence of asthma in children in Indonesia varies from 2.1% to 32.2% depends on location of the study, and method of study. However, the prevalence of asthma in children in central of Jakarta – polluted area were unknown. Methods: This study using the […]