Category archives for COPD

Effect of 250 mg Azithromycin Alternating Day on C-Reactive Protein in Stable Chronic Obstructive Pulmonary Disease

Meli Yusanti, Yusrizal Chan, Masrul Basyar, Yessy Susanty Sabri Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Andalas, Rumah Sakit Umum Pusat M.Djamil, Padang Abstract Background: COPD is a progressive respiratory disease with chronic inflammatory of the airway frequently accompanied by extra pulmonary symptoms. C reactive protein was one of the inflammatory marker with […]

Determinant of Bacterial Resistance to Antibiotics in Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)

Sri Hartati Handayani, Suradi, Reviono, Yusup Subagyo, Maryani Departemen Pulmonologi dan Ilmu Kedokteran Respirasi, Fakultas Kedokteran Universitas Sebelas Maret, Surakarta Abstract Backgrounds: Chronic obstructive pulmonary disease (COPD) is a major health problem in the community. Bacterial and viral infections increasing frequency of new bacterial strain exacerbations. The presence of bacterial colonization in the airways increased […]

Antibiotic Effects on Sputum Interleukin 8 (Il-8) Sputum and Dyspneu Scale in Stable Chronic Obstructive Pulmonary Disease

Yeni Putri, Taufik, Yusrizal Chan, Irvan Medison Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Andalas, Rumah Sakit Umum Pusat M. Djamil, Padang Abstract Backgrounds: Chronic Obstructive Pulmonary Disease (COPD) is a chronic inflammation of the airway that is persistent and progressive. Patient with stable COPD frequently have bacterial colonization in lower respiratory tract […]

Impact of Chemical Agent Exposure During Batik Colouring Process to Lung Clinical Impairment of Batik’s Industry Worker

Riana Sari, Suradi, Faisal Yunus Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Sebelas Maret, RSUD Dr. Moewardi, Surakarta Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta Abstract Background: Batik is a craft which has a high art and culture value to Indonesian especially Javanese. Chemical agents exposure at the batik coloring […]

Depression in Chronic Obstructive Pulmonary Disease Population and Correlation with Serum Level Interleukin (IL)-6 and Quality of Life

Jenny Wailan Kandowangko, Susanthy Djajalaksana, Harun Al Rasyid Abstract Background: Depression is a main comorbid in COPD and it is related with the decrease in health status and worse prognosis. There is also increase of abnormal inflammatory cells activation and increase of cytokine IL-6 during depression period. Methods: Observational cross sectional study, 36 stable COPD […]

Non Invasive Ventilation Role and Application in Chronic Obstructive Pulmonary Disease Exacerbation

Ferry Dwi Kurniawan, Prasenohadi, Faisal Yunus Abstract Chronic Obstructive Pulmonary Disease (COPD) exacerbation related to an increased risk of mortality, morbidity and health cost. Evidently, non invasive ventilation (NIV) has a role in reducing risk of in-hospital mortality, intubation and length of stay. By providing Positive End Expiratory Pressure (PEEP) extrinsically, it could overcome the […]

The Role of Modification of CURB-65 Score as Prediction Factor for One Year Survival in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Widya Sri Hastuti, Wiwien Heru Wiyono, Ratnawati, Iwang Gumiwang, Joedo Prihartono Abstract Introduction : Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is associated with a high risk of mortality. Cardiovascular disease is major cause of mortality in COPD. We hypothesized a risk-prediction model using modification of CURB-65 score (CURB-65 with cardiovascular disease) could predict risk […]

The Role of Symptom-based Questionnaire for Diagnosing Chronic Obstructive Pulmonary Disease. Evidence-based Case Report

Aghnia Permatasari, Dita Gemiana, Fitriana Nur, Raditya Ardi, Wahyu Permatasari, Jamal Zaini Abstract Background: Chronic obstructive pulmonary disease (COPD) diagnosis using spirometry in primary care is quite difficult due to the availability. The aim of this study is to evaluate diagnosis value of symptom-based questionnaire in COPD diagnosis. Methods: Literature search using Pubmed, SCOPUS, and EBSCO databases […]

Phenotypes of Chronic Obstructive Pulmonary Disease (COPD)

Mufidatun Hasanah, Susanthy Djajalaksana Abstract COPD is a complex syndrome with numerous pulmonary and extrapulmonary components with significant heterogeneity. The term phenotype in the field of COPD is defined as “a single or combination of disease attributes that describe differences between individuals with COPD as they relate to clinically meaningful outcomes”. Among all phenotypes identified, there are […]

Correlation of Quality of Life Assessment and Prognosis Chronic Obstructive Pulmonary Disease Patient with CAT, SGRQ and BODE at Persahabatan Hospital Jakarta

Tri Agus Yuarsa, Faisal Yunus, Budhi Antariksa Abstract Background : The health status is very important aspect in the evaluation of COPD management. St George’s respiratory questionnaire (SGRQ) is one of the tools to evaluate health status associated with quality of life in COPD that consist of symptoms, daily activity and impact of COPD. Currently […]

Editorial: Chronic Obstructive Pulmonary Disease (COPD): “GOLD Revised 2011” lebih aplikatif?

Djajalaksana S. J Respir Indo. 2012;32(4):198-9. Chronic obstructive pulmonary disease (COPD) atau disosialisasikan dengan bahasa Indonesia PPOK (penyakit paru obstruktif kronik) adalah penyakit paru yang dapat dicegah dan diobati, ditandai dengan limitasi aliran udara yang persisten dan progresif, akibat respons inflamasi kronik pada jalan  napas dan parenkim paru yang disebabkan gas atau partikel beracun. Eksaserbasi dan komorbid berkontribusi pada beratnya penyakit […]

Correlation Between The Degree of Breathlessness According to Modified Medical Research Council Scale (MMRC scale) with The Degree of Chronic Obstructive Pulmonary Disease

Anwar D, Chan Y, Basyar M. J Respir Indo. 2012;32(4):200-7. Abstract Background: Although spirometry should be undertaken in all patients who may have COPD, in many areas practitioners lack access to spirometry. MMRC scale questionnaire can be used to assess the breathlessness. The aim of this study was determine the association between the degree of […]

Comparison of Serum Testosterone and Growth Hormone in Stable Chronic Obstructive Pulmonary Disease Patients

Fachri M, Yunus F, Wiyono WH, Kekalih A. J Respir Indo.2012;32(4):208-17. Abstract Introduction: There is a correlation between the disturbance of endocrine glands and muscular weakness in COPD patients. Two hormones assumed to be affected are growth hormone and testosterone hormone. Methods: In observational case control study, we collected data consecutively from stable COPD patients […]

Characteristics of Acute Exacerbation COPD in Relation to Bacterial Sputum Culture Result at Dr. Moewardi Hospital Surakarta

Suradi, Sutanto YS, Reviono, Harsini, Marhendra D. J Respir Indo.2012;32(4):218-22. Abstract Background: Respiratory tract infections are the leading cause of acute exacerbation of COPD (AECOPD). The aim of this study was to investigate the frequency of bacterial infection, bacterial profile, antibiotics sensitivity and comparison of patient characteristics according to sputum culture. Methods: A cross sectional […]

Serum Desmosine Level in Stable Chronic Obstructive Pulmonary Diseases

Sholikhah S, Yunus F, Wiyono WH. J Respir Indo.2012;32(4):223-32 Abstract Background: There is a correlation between elastin and pathogenesis of COPD in COPD patients. Desmosine is intermolecular and intramolecular cross link between the chains of elastin polypeptide. Elastin is the main component of lung connective tissue that maintains the elasticity of the lung. If there […]

Effect of N-Acetyl Cysteine on Stable Chronic Obstructive Pulmonary Disease among Outpatients in Pulmonary Clinic in Dr. M. Djamil Hospital Padang

Suwarti SA, Chan Y, Zainoeddin ZY, Taufik, Khairsyaf O J Respir Indo. 2012;32:233-9 Abstract Background: Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease with airflow limitation that is not fully reversible. Tobacco smoke and air pollution can cause oxidative stress which contribute in cell and tissue damage. N-Acetylcysteine is an antioxidant that […]

Correlation of Sputum Macrophage and Neutrophil with COPD Assessment Test (CAT)

Wijaya o, Sartono TR, Djajalaksana S, Maharani A J Respir Indo.2012; 32(4):240-9 Abstract Introduction: The abnormality of COPD is caused by long standing inflammatory response, imbalance of proteinases and anti proteinases and increased oxidative stress in the airway. Increased airway inflammation will accelerate the decline in lung function and impair quality of life. This study […]

Ultra-Long Acting B2 Agonist (LABA) : Indacaterol for Chronic Obstructive Pulmonary Disease (COPD)

Amin M J Respir 1Indo. 2012; 32(4):250-4 Abstract Chronic Obstructive Pulmonary Disease (COPD) is characterised by progressive airflow limitation. According to Global Initiative forChronic Obstructive Lung Disease (GOLD), bronchodilators are the mainstay of therapy. The role of LABAs in the treatment of stable COPD, including bronchodilation and reduced air trapping resulting in improved lung function […]

Role of Aging and Cellular Senescence in Pathogenesis of COPD

Kurniawan FD, Andarini SL, Yunus F. J Respir Indones. 2011;31(4):224-32. Abstract Chronic Obstructive Pulmonary Disease (COPD) prevalence in the elderly is increasing. During aging, lung structure and function deteriorate and increase pathogenetic susceptibility to COPD. Aging is a progressive decline of homeostasis that occurs after the reproductive phase of life is complete and leading to […]

Terapi Pasien Asma Perokok: Peranan Teofilin Dosis Rendah

Rai IBN. J Respir Indones. 2009;29(4). We often find outpatient asthma patient smoking. Actively smoking asthma patient showed more severe symptom and more frequent attack than non smoking group of patient. Cigarette smoking induced neutrophilic inflammation in asthma patients airway. Beside that, decreased sensitivity to inhaled or oral corticosteroid treatment also plays very important role […]

Efek Peradangan Sistemik Pada PPOK Terhadap Sistem Kardiovaskular

Fahri I, Sutoyo DK, Yunus F. J Respir Indones. 2009;29(3). Penyakit Paru Obstruktif Kronik (PPOK) adalah kondisi penyakit yang dapat dicegah dan diobati dengan karakteristik berupa keterbatasan aliran udara yang tidak sepenuhnya reversibel. Keterbatasan aliran udara bersifat progresif dan berkaitan dengan reaksi peradangan paru terhadap partikel atau gas berbahaya, terutama disebabkan oleh asap rokok. Penyakit […]

Hubungan Merokok dan Lama Rawat Inap Pasien Asma Eksaserbasi Akut Di RSUP Sanglah Denpasar

Rai IBN, Sajinadiyasa IGK. J Respir Indones. 2009;29(3). In most developed countries ±25% of adults with asthma are current cigarette smokers. Asthma and cigarette smoking interact to cause more severe symptoms, accelerated decline in lung function, and impaired short-term therapeutic response to corticosteroids. One of variable to evaluation response of treatment was length of stay. […]

Manfaat Rehabilitasi Paru dalam Meningkatkan atau Mempertahankan Kapasitas Fungsional dan Kualitas Hidup Pasien Penyakit Paru Obstruktif Kronik di RSUP Persahabatan

Abidin A, Yunus F, Wiyono WH, Ratnawati A. J Respir Indones. 2009;29(2). Study objective: A prospective study to investigate of pulmonary rehabilitation program may increase or maintains quality of life and functional capacity in patients with mild to moderate COPD. Design: Randomized control trial Method: We conducted a randomized controlled trials of outcome assessment and […]

Prevalensi Gangguan Obstruksi Paru dan Faktor-Faktor yang Berhubungan pada Pekerja Dermaga & Silo Gandum di PT X Jakarta

Aviandari G, Budiningsih S, Ikhsan M. J Respir Indones. 2009;29(2). Background: Respiratory disesase is related to exposure wheat grain dust. Increase consumption of wheat flour will increase activity wheat grain handling at Jetty and wheat Silo in X company in Jakarta. This situation may increased the prevalence of obstructive lung disease. Objective: The aim of […]