Interventional Approach on Lung Abscess

Dea Putri Audina, Heidy Agustin, Tina Reisa


Lung abscess is a necrotic liquefaction process containing necrotic debris or fluid from the lung parenchyma tissue, creating a cavity of more than 2 cm caused by bacterial infection. The most common etiology of lung abscess is oral aspiration. With a high incidence of tuberculosis in Indonesia, Mycobacterium tuberculosis may also cause cold abscesses, although rarely reported. Several things can increase the risk of developing a lung abscess, such as oral aspiration, sepsis, and history of previous lung infection. The treatment for lung abscess was classified into two groups, the pharmacology group which uses antibiotics including clindamycin, ampicillin-sulbactam, moxifloxacin, carbapenem, and piperacillin-tazobactam; and the other group is non-pharmacology therapy including drainage which is indicated for patient with a size cavity of more than 6 cm. There are several options for drainage such as percutaneous or endoscopic drainage. Bronchoscopy may serve as a diagnostic and also intervention tool in lung abscess.


Lung abscess, Lung cavity, Lung abscess treatment

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Rahmawati I, Pinastika RA, Wicaksono RB. Lung abscess as a delayed complication in a COVID-19 pneumonia patient: A case report. Jurnal Respirasi. 2022;8(3):161–8.

Huang HC, Chen HC, Fang HY, Lin YC, Wu CY, Cheng CY. Lung abscess predicts the surgical outcome in patients with pleural empyema. J Cardiothorac Surg. 2010;5:88.

Lawrensia S. Lung abscess: Diagnosis and treatment. Cermin Dunia Kedokteran. 2021;48(5):286–8.

Mustafa M, Iftikhar HM, Hamid SA, Ootha N. Lung abscess: Diagnosis, treatment and mortality. International Journal of Pharmaceutical Science Invention ISSN. 2015;4(2):37–41.

Takayanagi N, Kagiyama N, Ishiguro T, Tokunaga D, Sugita Y. Etiology and outcome of community-acquired lung abscess. Respiration. 2010;80(2):98–105.

Allewelt M. Aspiration pneumonia and primary lung abscess: Diagnosis and therapy of an aerobic or an anaerobic infection? Expert Rev Respir Med. 2007;1(1):111–9.

Tutar N, Oymak FS, Kanbay A, Büyükoǧlan H, Yildirim A, Yilmaz I, et al. Lung abscess: Analysis of the results as community-acquired or nosocomial. Turk J Med Sci. 2013;43(2):255–62.

Sethi S. Lung abscess - Pulmonary disorders [Internet]. MSD Manual Professional Edition. 2021 [cited 2022 May 2]. Available from:

Sabbula BR, Rammohan G, Athavale A, Akella J. Lung abscess. Encyclopedia of Respiratory Medicine: Volume 1-4. 2023;1–4:V2-600-V2-606.

Kuhajda I, Zarogoulidis K, Tsirgogianni K, Tsavlis D, Kioumis I, Kosmidis C, et al. Lung abscess-etiology, diagnostic and treatment options. Vol. 3, Annals of Translational Medicine. 2015. p. 183.

Mohammad M, Na M, Hu Z, Nguyen MT, Kopparapu PK, Jarneborn A, et al. Staphylococcus aureus lipoproteins promote abscess formation in mice, shielding bacteria from immune killing. Commun Biol. 2021;4:432.

Grippi MA, Elias JA, Fisherman JA, Kotloff RM, Pack AI, Senior RM. Fishman’s pulmonary disease and disorders. 5th ed. McGraw-Hill Education. McGraw-Hill Education; 2015.

Loscalzo J. Harrison’s pulmonary and critical care medicine. 3rd ed. Vol. 273, JAMA: The Journal of the American Medical Association. New York: McGraw Hill Education; 2016.

Eira IM, Carvalho R, Carvalho DV, Ângela C. Lung abscess in an immunocompromised patient: Clinical presentation and management challenges. BMJ Case Reports. 2019;12:e230756.

Unterman A, Fruchter O, Rosengarten D, Izhakian S, Abdel-Rahman N, Kramer MR. Bronchoscopic drainage of lung abscesses using a pigtail catheter. Respiration. 2017;93(2):99–105.

Browning RF, Turner JF, Wang KP. Indications and contraindications in flexible bronchoscopy. Flexible Bronchoscopy. 2012;70–91.

Lin Q, Jin M, Luo Y, Zhou M, Cai C. Efficacy and safety of percutaneous tube drainage in lung abscess: A systematic review and meta-analysis. Expert Rev Respir Med. 2020;14(9):949–56.

Cascone R, Sica A, Sagnelli C, Carlucci A, Calogero A, Santini M, et al. Endoscopic treatment and pulmonary rehabilitation for management of lung abscess in elderly lymphoma patients. Int J Environ Res Public Health. 2020;17(3):997.

Wali SO. An update on the drainage of pyogenic lung abscesses. Ann Thorac Med. 2012;7(1):3.

Matarese A, Tamburrini M, Desai U, Zuccon U. Percutaneous lung abscess drainage: Revisiting the old gold standard. Monaldi Archives for Chest Disease. 2020;90(1):113–8.

Huret B, Boulanger S. Transbronchial drainage of a central lung abscess using linear endobronchial ultrasonography. Journal of Bronchology and Interventional Pulmonology. 2021;28:300–2.

Yaguchi D, Ichikawa M, Inoue N, Kobayashi D, Shizu M, Imai N. Transbronchial drainage using endobronchial ultrasonography with guide sheath for lung abscess: A case report. Medicine (United States). 2018;97(20).

Schweigert M, Dubecz A, Beron M, Ofner D, Stein H. Surgical therapy for necrotizing pneumonia and lung gangrene. Thoracic and Cardiovascular Surgeon. 2013;61(7):636–41.

Kaple GS, Yadav V, Jain M, Bhakney P, Vardhan V. Tailor-made pulmonary rehabilitation program aiding return to preinfection fitness in massive cavitatory lung abscess: A case report. Journal of Clinical and Diagnostic Research. 2022;16(9):YD01–3.

Yousef L, Yousef A, Al-Shamrani A. Lung abscess case series and review of the literature. Children. 2022;9(7):1047.



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Jurnal Respirologi Indonesia
pISSN: 0853-7704 - eISSN: 2620-3162
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