The Diagnostic Role of Narrow-Band Imaging Bronchoscopy For Early Detection of Lung Adenocarcinoma in a Young Adult

Authors

DOI:

https://doi.org/10.36497/jri.v45i2.649

Keywords:

bronchoscopy, diagnosis, lung adenocarcinoma

Abstract

Background: Lung adenocarcinoma is a common type of cancer that is typically associated with older individuals who have a history of smoking. However, in some rare cases, this occurs in young adults.

Case: This case report discusses the diagnostic challenges and the important role of bronchoscopy in confirming lung adenocarcinoma in a 35-year-old male patient with a history of smoking. The patient had a persistent cough and unexplained weight loss. This raised concerns about various differential diagnoses, such as infectious diseases, abnormalities in the bronchial tree, and rare lung neoplasms. In this case report, we used a combination of White Light Bronchoscopy (WLB) and the Narrow Band Imaging (NBI) technique to identify pre-cancerous lesions and early-stage cancers within the airways.

Discussion: This case report highlights the significance of bronchoscopy as a diagnostic tool for lung cancer in unexpected populations like young adults. The successful diagnosis through bronchoscopy led to prompt treatment initiation.

Conclusion: This case underscores the importance of a multidisciplinary approach to lung cancer diagnosis and management, adapting to the unique situations of individual patients.

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Author Biographies

  • Christina Siuwandy Bu'ulolo, Department of Pulmonology and Respiratory Medicine, Wangaya Hospital, Denpasar
    Department of Pulmonology and Respiratory Medicine
  • Wayan Wahyu Semaraputra, Department of Pulmonology and Respiratory Medicine, Wangaya Hospital, Denpasar
    Department of Pulmonology and Respiratory Medicine
  • Novitasari Novitasari, Department of Pathology Anatomy, Wangaya Hospital, Denpasar
    Department of Pathological Anatomy

References

1. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394-424.

2. Zheng M. Classification and Pathology of Lung Cancer. Surg Oncol Clin N Am. 2016;25(3):447-468.

3. Sayed E, Gawad A El, Awad T, Taha T. Unusual presentation of lung cancer in young patient: case report. Egypt J Bronchol. 2024;18:44.

4. Almodovar T, Teixeira E, Barroso A, et al. Elderly patients with advanced NSCLC: the value of geriatric evaluation and the feasibility of CGA alternatives in predicting chemotherapy toxicity. Pulmonology. 2019;25(1):40-50.

5. Ning J, Ge T, Jiang M, et al. Early diagnosis of lung cancer: which is the optimal choice? Aging. 2021;13(4):6214-6227.

6. Aberle DR, Black WC, Chiles C, et al. Lung cancer incidence and mortality with extended follow-up in the National Lung Screening Trial National Lung Screening Trial Writing Team. J Thorac Oncol. 2019;14(10):1732-1742.

7. Aljuba AA, Mustafa Shawer B, Aljuneidi RM, et al. Central lung adenocarcinoma in a young male mimicking pneumonia with nonrecurrent polyserous effusions of negative cytology: a case report. Medicine. 2024;103(31):e39189.

8. Becker N, Motsch E, Trotter A, et al. Lung cancer mortality reduction by LDCT screening—results from the randomized German LUSI trial. Int J Cancer. 2020;146(6):1503-1513.

9. Hoffman RM, Atallah RP, Struble RD, Badgett RG. Lung cancer screening with low-dose CT: a meta-analysis. J Gen Intern Med. 2020;35(10):3015-3025.

10. Andolfi M, Potenza R, Capozzi R, Liparulo V, Puma F, Yasufuku K. The role of bronchoscopy in the diagnosis of early lung cancer: a review. J Thorac Dis. 2016;8(11):3329-3337.

11. Zhang J, Wu J, Yang Y, et al. White light, autofluorescence and narrow-band imaging bronchoscopy for diagnosing airway pre-cancerous and early cancer lesions: a systematic review and meta-analysis. J Thorac Dis. 2016;8(11):3205-3216.

12. Zhu J, Li W, Zhou J, et al. The diagnostic value of narrow-band imaging for early and invasive lung cancer: a meta-analysis. Clinics (Sao Paulo). 2017;72(7):438-448.

13. Elhidsi M, Zaini J, Soehardiman D, Pradono P, Rasmin M. Accuracy of narrow-band imaging bronchoscopy for early diagnosis of airway cancer lesions: a systematic review and meta-analysis. Int J Cancer Manag. 2023;16(1):e133783.

14. Elhefny RA, Elessawy AF, Beih SSA, Ali MA, Ahmed MI. Comparison of narrow band imaging to white light bronchoscopy for evaluation of histopathological biopsy. Egypt J Chest Dis Tuberc. 2016;65(1):341-347.

15. Zhu J, Liu R, Wu X, et al. The value of narrow-band imaging bronchoscopy in diagnosing central lung cancer. Front Oncol. 2022;12:998770.

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Published

2025-04-20

Issue

Section

Case Report

How to Cite

The Diagnostic Role of Narrow-Band Imaging Bronchoscopy For Early Detection of Lung Adenocarcinoma in a Young Adult. (2025). Jurnal Respirologi Indonesia, 45(2), 144-149. https://doi.org/10.36497/jri.v45i2.649

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