Ferry Dwi Kurniawan, Prasenohadi, Faisal Yunus
Chronic Obstructive Pulmonary Disease (COPD) exacerbation related to an increased risk of mortality, morbidity and health cost. Evidently, non invasive ventilation (NIV) has a role in reducing risk of in-hospital mortality, intubation and length of stay. By providing Positive End Expiratory Pressure (PEEP) extrinsically, it could overcome the intrinsic PEEP which derived from increasing airway resistance and dynamic hyperinflation. Patients selection, ventilator and mask availability, ventilator setting and monitoring, should be considered during NIV application. This literature review will discuss NIV role and its application in COPD exacerbation. (J Respir Indo. 2014; 34: 53-9)
Key words: COPD, non-invasive ventilation, PEEP.