Tag archives for copd

Prevalence of Depression in Outward COPD Patients Based on Mini International Neuropsychiatric Interview Version ICD-10

Nurfitriani Usman,1 Faisal Yunus,1 Tribowo Tuahta Ginting2 1Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta 2Departemen Ilmu Kedokteran Jiwa, Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta Abstract Background: Patients with COPD typically elderly, have comorbid diseases and their significant relations with their smoking history. One of the most frequent comorbid in […]

Effect of Simvastatin Against Serum levels of MMP-9 and Values FEV1% in Stable COPD

Indah Juliana, Suradi, Ana Rima Setijadi Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Sebelas Maret, RSUD Dr. Moewardi, Surakarta Abstract Background: Inflammation of COPD is persistent and progressive. Chronic inhalation of cigarette smoke causes the neutrophil infiltration into the airways, release cytokines, proinflammatory chemokines and proteases, especially MMP-9. Structural abnormalities lead to hyperinflation and […]

The Role of Xanthine in Pulmonary Obstructive Disease

Budi Yanti,1 Menaldi Rasmin2 1SMF Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Syiah Kuala, RSUD Dr. Zainoel Abidin, Banda Aceh 2 Departemen Pulmonologi dan Kedokteran Respirasi Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta Abstract Theophylline has been used in the treatment of asthma and chronic obstructive pulmonary disease (COPD) for over 60 years and remains […]

Prevalence of Obstructive Sleep Apnea (OSA) in Patients with Mild to Severe COPD Based on Berlin Questionnaire and Polysomnography

Ratih Pahlesia,1 Faisal Yunus,1 Budhi Antariksa,1 Ratnawati,1 Dody Widodo1 1Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta 2Departemen THT Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta Abstract Background: Patients with COPD may have a concomitant sleep apnea that can further exacerbate their gas exchange during sleep. They have an increased risk […]

The Relationship between Smoking Cessation with The Severity of Chronic Obstructive Pulmonary Disease Based on GOLD 2013

Danar Pratama Putra, Nurfitri Bustamam, Aulia Chairani Fakultas Kedokteran Universitas Pembangunan Nasional Veteran, Jakarta Abstract Background: Smoking is responsible for approximately 90% of COPD. Smoking cessation is one of nonpharmacological managements for COPD patient. This study was aimed to determine the relationship between smoking cessation and the severity of COPD based on GOLD 2013. Methods: […]

Metabolic Syndrome in Chronic Obstructive Pulmonary Disease (COPD)

Iceu Dimas Kulsum, Faisal Yunus Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta Abstract Metabolic syndrome is a complex disorder and an emerging clinical challenge, recognized clinically by the findings of abdominal obesity, elevated triglycerides, atherogenic dyslipidemia, elevated blood pressure, high blood glucose and/or insulin resistance. Metabolic syndrome is 1.5-3 times […]

Increase of Malondialdehyde Serum Level After Pulmonary Rehabilitation Reduce Depression and Improve Quality of Life in Chronic Obstructive Pulmonary Disease Patients

Dewi Kartikaningsih, Susanthy Djajalaksana, Moch. Ridwan, Harun Al Rasyid Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Brawijaya, Malang Departemen Ilmu Kedokteran Fisik dan Rehabilitasi, Fakultas Kedokteran Universitas Brawijaya, Malang Departemen Ilmu Kesehatan Masyarakat, Fakultas Kedokteran Universitas Brawijaya, Malang Abstract Background: Depression is a major comorbid for COPD patients and associated with decline in health […]

COPD Assesment Test Score, Modified Medical Research Council Dyspnea Scale With Forced Expiratory Volume In One Second and Exacerbation Risk In Stable COPD

Dewi Manihuruk, Pandiaman Pandia, Amira Tarigan, Putri Chairani Eyanoer Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Sumatera Utara, RSUP H. Adam Malik Medan Abstract Background: COPD is considered as a complex disease and global problem that is predicted to be the third most common cause of death by 2030. The 2014 GOLD (Global Strategy for […]

Differences Between Upper Limb and Lower Limb Exercise to Training Capacity and Fat-Free Mass of Stable Chronic Obstructive Pulmonary Disease Patients

Zakiah Novianti¹, Suradi¹, Muchsin Doewes² ¹Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Sebelas Maret ²Departemen Kedokteran Olahraga, Fakultas Kedokteran Universitas Sebelas Maret Abstract Backgound: Exercise intolerance is one of the main factors limiting participation in activities of daily living among individuals with chronic obstructive pulmonary disease (COPD). Depletion of fat-free mass (FFM) significantly contributes […]

Assosiation between Sputum Interleukin 8 Level with Bacterial Colonisation in Lower Respiratory Tract and Disease Severity in Stable COPD

Ruri Intania, Taufik, Yusrizal Chan, Irvan Medison Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Andalas, RSUP Dr. M. Djamil, Padang Abstract Background: Lung damage facilitates the colonization of pathogenic bacteria in lower respiratory tract of COPD patients that induces inflammation of which indeed exacerbation, thus contributing to the progression of obstruction which is […]

Azithromycin Towards COPD Assesment Test (CAT) for Stable Chronic Obstructive Pulmonary Disease

Hendri Nofa, Yusrizal Chan, Masrul Basyar, Oea Khairsyaf Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Andalas, RSUP Dr. M. Djamil, Padang Abstract Background: Azithromycin is a macrolide, that have antibiotic anti inflammation property that might decrease progresivity of chronic obstructive pulmonary disease (COPD). CAT is a simple questionnaire, useful and sensitive for the […]

Effect of 250 mg Azithromycin Alternating Day on C-Reactive Protein in Stable Chronic Obstructive Pulmonary Disease

Meli Yusanti, Yusrizal Chan, Masrul Basyar, Yessy Susanty Sabri Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Andalas, Rumah Sakit Umum Pusat M.Djamil, Padang Abstract Background: COPD is a progressive respiratory disease with chronic inflammatory of the airway frequently accompanied by extra pulmonary symptoms. C reactive protein was one of the inflammatory marker with […]

Antibiotic Effects on Sputum Interleukin 8 (Il-8) Sputum and Dyspneu Scale in Stable Chronic Obstructive Pulmonary Disease

Yeni Putri, Taufik, Yusrizal Chan, Irvan Medison Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Andalas, Rumah Sakit Umum Pusat M. Djamil, Padang Abstract Backgrounds: Chronic Obstructive Pulmonary Disease (COPD) is a chronic inflammation of the airway that is persistent and progressive. Patient with stable COPD frequently have bacterial colonization in lower respiratory tract […]

Depression in Chronic Obstructive Pulmonary Disease Population and Correlation with Serum Level Interleukin (IL)-6 and Quality of Life

Jenny Wailan Kandowangko, Susanthy Djajalaksana, Harun Al Rasyid Abstract Background: Depression is a main comorbid in COPD and it is related with the decrease in health status and worse prognosis. There is also increase of abnormal inflammatory cells activation and increase of cytokine IL-6 during depression period. Methods: Observational cross sectional study, 36 stable COPD […]

Non Invasive Ventilation Role and Application in Chronic Obstructive Pulmonary Disease Exacerbation

Ferry Dwi Kurniawan, Prasenohadi, Faisal Yunus Abstract Chronic Obstructive Pulmonary Disease (COPD) exacerbation related to an increased risk of mortality, morbidity and health cost. Evidently, non invasive ventilation (NIV) has a role in reducing risk of in-hospital mortality, intubation and length of stay. By providing Positive End Expiratory Pressure (PEEP) extrinsically, it could overcome the […]

The Role of Symptom-based Questionnaire for Diagnosing Chronic Obstructive Pulmonary Disease. Evidence-based Case Report

Aghnia Permatasari, Dita Gemiana, Fitriana Nur, Raditya Ardi, Wahyu Permatasari, Jamal Zaini Abstract Background: Chronic obstructive pulmonary disease (COPD) diagnosis using spirometry in primary care is quite difficult due to the availability. The aim of this study is to evaluate diagnosis value of symptom-based questionnaire in COPD diagnosis. Methods: Literature search using Pubmed, SCOPUS, and EBSCO databases […]

Phenotypes of Chronic Obstructive Pulmonary Disease (COPD)

Mufidatun Hasanah, Susanthy Djajalaksana Abstract COPD is a complex syndrome with numerous pulmonary and extrapulmonary components with significant heterogeneity. The term phenotype in the field of COPD is defined as “a single or combination of disease attributes that describe differences between individuals with COPD as they relate to clinically meaningful outcomes”. Among all phenotypes identified, there are […]

Correlation Between The Degree of Breathlessness According to Modified Medical Research Council Scale (MMRC scale) with The Degree of Chronic Obstructive Pulmonary Disease

Anwar D, Chan Y, Basyar M. J Respir Indo. 2012;32(4):200-7. Abstract Background: Although spirometry should be undertaken in all patients who may have COPD, in many areas practitioners lack access to spirometry. MMRC scale questionnaire can be used to assess the breathlessness. The aim of this study was determine the association between the degree of […]

Comparison of Serum Testosterone and Growth Hormone in Stable Chronic Obstructive Pulmonary Disease Patients

Fachri M, Yunus F, Wiyono WH, Kekalih A. J Respir Indo.2012;32(4):208-17. Abstract Introduction: There is a correlation between the disturbance of endocrine glands and muscular weakness in COPD patients. Two hormones assumed to be affected are growth hormone and testosterone hormone. Methods: In observational case control study, we collected data consecutively from stable COPD patients […]

Characteristics of Acute Exacerbation COPD in Relation to Bacterial Sputum Culture Result at Dr. Moewardi Hospital Surakarta

Suradi, Sutanto YS, Reviono, Harsini, Marhendra D. J Respir Indo.2012;32(4):218-22. Abstract Background: Respiratory tract infections are the leading cause of acute exacerbation of COPD (AECOPD). The aim of this study was to investigate the frequency of bacterial infection, bacterial profile, antibiotics sensitivity and comparison of patient characteristics according to sputum culture. Methods: A cross sectional […]

Serum Desmosine Level in Stable Chronic Obstructive Pulmonary Diseases

Sholikhah S, Yunus F, Wiyono WH. J Respir Indo.2012;32(4):223-32 Abstract Background: There is a correlation between elastin and pathogenesis of COPD in COPD patients. Desmosine is intermolecular and intramolecular cross link between the chains of elastin polypeptide. Elastin is the main component of lung connective tissue that maintains the elasticity of the lung. If there […]

Effect of N-Acetyl Cysteine on Stable Chronic Obstructive Pulmonary Disease among Outpatients in Pulmonary Clinic in Dr. M. Djamil Hospital Padang

Suwarti SA, Chan Y, Zainoeddin ZY, Taufik, Khairsyaf O J Respir Indo. 2012;32:233-9 Abstract Background: Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease with airflow limitation that is not fully reversible. Tobacco smoke and air pollution can cause oxidative stress which contribute in cell and tissue damage. N-Acetylcysteine is an antioxidant that […]

Correlation of Sputum Macrophage and Neutrophil with COPD Assessment Test (CAT)

Wijaya o, Sartono TR, Djajalaksana S, Maharani A J Respir Indo.2012; 32(4):240-9 Abstract Introduction: The abnormality of COPD is caused by long standing inflammatory response, imbalance of proteinases and anti proteinases and increased oxidative stress in the airway. Increased airway inflammation will accelerate the decline in lung function and impair quality of life. This study […]

Ultra-Long Acting B2 Agonist (LABA) : Indacaterol for Chronic Obstructive Pulmonary Disease (COPD)

Amin M J Respir 1Indo. 2012; 32(4):250-4 Abstract Chronic Obstructive Pulmonary Disease (COPD) is characterised by progressive airflow limitation. According to Global Initiative forChronic Obstructive Lung Disease (GOLD), bronchodilators are the mainstay of therapy. The role of LABAs in the treatment of stable COPD, including bronchodilation and reduced air trapping resulting in improved lung function […]

Role of Aging and Cellular Senescence in Pathogenesis of COPD

Kurniawan FD, Andarini SL, Yunus F. J Respir Indones. 2011;31(4):224-32. Abstract Chronic Obstructive Pulmonary Disease (COPD) prevalence in the elderly is increasing. During aging, lung structure and function deteriorate and increase pathogenetic susceptibility to COPD. Aging is a progressive decline of homeostasis that occurs after the reproductive phase of life is complete and leading to […]