Risk Factors for Mortality of Patients with Covid-19 in RSJPD Harapan Kita, Jakarta
Abstract
Abstract
Background:TheCovid-19 disease has caused significant morbidity and mortality worldwide since Covid-19 was first reported in December 2019. More intense kinds of the disorder main to loss of life arise greater regularly in older sufferers and people with more than one comorbidities. This study aims to determine the risk factors associated with death in Covid-19 patients at RSJPD Harapan Kita.
Methods:A total of 500 patients with a positive result on the Covid-19 polymerase-chain-reaction (PCR) test from RSJPD Harapan Kita were analyzed. The Demographic, clinical, and outcome data were extracted from the hospital's medical record system. To explore the risk factors associated with mortality, univariable and multivariable logistic regression analyses were used.
Results:Of the 500 patients included in this study, 110 (22%) died in the hospital. The multivariate regression analysis showed that age³65 years (adjusted odds ratio (aOR), 2,624; (95% CI: 1,552 – 4,435), chronic lung disease (aOR, 8,173; 95% CI: 3,834 – 17,422), chronic kidney disease (aOR,2,523; 95% CI: 1,358 – 4,689), and cardiovascular disease (aOR, 3,149; 95% CI: 1,763 – 5,624) had been recognized as risk factors of mortality among Covid-19 patients.
Conclusion: Age ³65 years, chronic lung disease, chronic kidney disease patients, and cardiovascular disease had been recognized as risk factors of mortality among Covid-19 patients in RSJPD Harapan Kita. More research on the risk factors related to Covid-19-associate death is had to manage ailment development and to enhance its treatment.
Keywords: Covid-19, Risk Factors, Mortality, Comorbidities.
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Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054–62.
World Health Organization. WHO Coronavirus (COVID-19) Dashboard [Internet]. World Health Organization. 2022 [cited 2022 Mar 9]. Available from: https://covid19.who.int
Kementerian Kesehatan RI. Covid-19 [Internet]. Kementerian Kesehatan RI. 2022 [cited 2022 Mar 9]. Available from: https://infeksiemerging.kemkes.go.id/dashboard/covid-19
Sanyaolu A, Okorie C, Marinkovic A, Patidar R, Younis K, Desai P, et al. Comorbidity and its Impact on Patients with COVID-19. SN Compr Clin Med. 2020;2(6):1069–76.
Albitar O, Ballouze R, Ooi JP, Sheikh Ghadzi SM. Risk factors for mortality among COVID-19 patients. Diabetes Res Clin Pract. 2020;166.
Imam Z, Odish F, Gill I, O’Connor D, Armstrong J, Vanood A, et al. Older age and comorbidity are independent mortality predictors in a large cohort of 1305 COVID-19 patients in Michigan, United States. J Intern Med. 2020;288(4):469–76.
Wu C, Chen X, Cai Y, Xia J, Zhou X, Xu S, et al. Risk Factors Associated with Acute Respiratory Distress Syndrome and Death in Patients with Coronavirus Disease 2019 Pneumonia in Wuhan, China. JAMA Intern Med. 2020;180(7):934–43.
Wasityastuti W, Dhamarjati A, Siswanto. Imunosenesens dan Kerentanan Populasi Usia Lanjut Terhadap Coronavirus Disease 2019 (Covid-19). Respirologi Indones. 2019;40(3):182–91.
Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ. COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet. 2020;395(10229):1033–4.
Ferguson J, Rosser JI, Quintero O, Scott J, Subramanian A, Gumma M, et al. Characteristics and outcomes of coronavirus disease patients under nonsurge conditions, Northern California, USA, March–April 2020. Emerg Infect Dis. 2020;26(8):1679–85.
Mallia P, Message SD, Gielen V, Contoli M, Gray K, Kebadze T, et al. Experimental rhinovirus infection as a human model of chronic obstructive pulmonary disease exacerbation. Am J Respir Crit Care Med. 2011;183(6):734–42.
Surendra H, Elyazar IR, Djaafara BA, Ekawati LL, Saraswati K, Adrian V, et al. Clinical characteristics and mortality associated with COVID-19 in Jakarta, Indonesia: A hospital-based retrospective cohort study. Lancet Reg Heal - West Pacific. 2021;9:100108.
Ortiz A, Cozzolino M, Duivenvoorden R, Fliser D, Fouque D, Franssen CFM, et al. Chronic kidney disease is a key risk factor for severe COVID-19: A call to action by the ERA-edta. Nephrol Dial Transplant. 2021;36(1):87–94.
Betjes MGH. Immune cell dysfunction and inflammation in end-stage renal disease. Nat Rev Nephrol. 2013;9(5):255–65.
Bonow R, Fonarow G, O’Gara P, Yancy C. Association of Coronavirus Disease 2019 (COVID-19) With Myocardial Injury and Mortality. JAMA - J Am Med Assoc. 2020;5(7):751–3.
DOI: https://doi.org/10.36497/jri.v42i2.287
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