Longitudinal Study Of BODE Index As Predictive Factor of COPD In Persahabatan Hospital Jakarta

Isep Supriyana, Faisal Yunus, Budhi Antariksa, Aria Kekalih

Abstract


Background: The BODE index is generally used for predicting mortality risk of COPD patients. The BODE index included the body mass index, degree of airflow obstruction (FEV1), dyspnea (MMRC questionnaire), and exercise capacity (6-minute walk test). Exacerbation of COPD associated with decreased health related quality of life (HRQoL). HRQoL has become an important outcome in respiratory patients as proved by St.George’s Respiratory Questionnaire (SGRQ). We hypothesized that the greater BODE score the more frequent occurrence of exacerbation and decreased HRQol.
Methods: Prospective cohort study of COPD patients in Persahabatan Hospital assessed for BODE index (baseline) and followed at 3, 6, 9 and 12 months. Patient were also examined with SGRQ at baseline and followed at 6 and 12 months. We monitored the occurrence of exacerbation every month by telephone, observed medical record, or visiting to COPD’s clinic and emergency unit.
Results: Eighty five patient were examined at baseline with mean of BODE index 4.29 and SGRQ total score 41.42%. After one year monitored 52 patients have completed examination, 29 patient have not complete examination and four patient died. Using t-test analysis the correlation of BODE index between single and frequent exacerbation is significant (p<0.05), the correlation of SGRQ between single and frequent exacerbation is also significant (p<0.05) and correlation between BODE and SGRQ is significant (p=0.045).
Conclusion: BODE index can predict COPD exacerbations and HRQol

Keywords


Exacerbation, BODE index, HRQoL

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DOI: https://doi.org/10.36497/jri.v39i4.75

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Jurnal Respirologi Indonesia
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