Analysis of Demographic Factor, Vital Sign, Degree of Symptom, Laboratorium Result and Comorbidity To Clinical Outcome of COVID-19 Patients In RSUDZA Banda Aceh

Heliyana Isma, Yunita Arliny, Dewi Behtri Yanifitri, Budiyanti Budiyanti, Teuku Zulfikar

Abstract


Background: Coronavirus disease (COVID-19) is an infectious disease caused by SARS-CoV-2 which leads to respiratory to systemic symptoms, it became pandemic until current. Clinical outcome of patients are varied depend to several factors. Methods: This study aimed to analyze clinical outcome, whether good or bad outcome of COVID-19 patients which related to demographic factors, vital signs, degree of symptom, laboratorium result and comorbidity. This study was an observational analytic study with cross sectional design. The samples were collected by total sampling method. All variables were analyzed toward medical record while admission. Bivariable and multivariable analysis were done to identify which factor who were most influence the clinical outcome of inhospital COVID-19 patients.

Results: Of 183 COVID-19 patients who were admitted, there were 80 patients (43,72%) with moderate degree, 77 patients

(42,08%) with severe degree and 26 patients (14,21%) were critically ill.There were 80 patients (43,72%) who had no

comorbidity and the rest were hypertension and cardiovascular disease in 39 patients (21,31%), diabetes melitus in 37 patients (20,22%), CKD in 13 patients (7,10%), COPD in 3 patients (1,64%), and other diseases in 11 patients (6,01%). There were significantly corelation among comorbidity and clinical outcome (p<0,001). Of demographic factors, age has been corelated to clinical outcome (p<0,001). Of vital sign variable, only blood pressure and heart rate who were corelated to clinical outcome (p=0,020 and p<0,001, respectively). Of laboratorium result, hemoglobin, leucocyte, random blood glucose and creatinine were corelated to clinical outcome (p=0,030, p=0,001, p<0,001, p<0,001 respectively). Multivariable analysis were done to show that severe degree of COVID-19 were most influenced toward clinical outcome with OR 5,6 (95%CI 2,223-13,90).

Conclusion: Age, comorbidity, blood pressure, heart rate, hemoglobin, random blood glucose and creatinin at admission are factors that influence clinical outcome of admitted COVID-19 patients.

Keywords


COVID-19, clinical outcome, demographic, vital signs, degree of symptoms, laboratorium result, comorbidity

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DOI: https://doi.org/10.36497/jri.v42i4.288

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Jurnal Respirologi Indonesia
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