Type 2 Diabetes Mellitus And Hemoptisis Risk Factor In Lung Tuberculosis : A Case Control Study
DOI:
https://doi.org/10.36497/jri.v40i3.111Keywords:
Tuberculosis, Diabetes Mellitus, HemoptysisAbstract
Background: Diabetes mellitus (DM) is a risk factor for tuberculosis (TB) morbidity and mortality. Increasing cases of type 2 DM in the world increases the risk of developing TB. The frequency of DM in TB patients was reported to be around 10-15% and the prevalence of this infectious disease was 2-5 times higher in diabetic patients compared to non-diabetics. Hemoptysis is a respiratory symptom which can be life threatening. Tuberculosis and bronchiectasis are the two most common ethology of hemoptysis, while TB with DM are the cause of recurrent hemoptysis. Methods: This was case control study which used the medical records data of diabetic patients infected with TB who experienced hemoptysis and no hemoptysis, treated at Fatmawati General Hospital during 2017. Sampling method was total sampling. Results: There were 12 hemoptysis patients with DM comorbidity and 31 patients without DM comorbidity. As many as 58% of patients with DM had new cases of pulmonary TB and 42% had history of treatment completion. The correlation between hemoptysis of TB patients with DM compared to without DM obtained a relative risk of 1.535 (95% CI=0.677-2.618) Conclusion: The proportion of hemoptysis in TB patients with DM comorbidity was 10.3%. Diabetes Mellitus was a risk factor for hemoptysis 1.535 times higher compared to TB patients without DM but statistically not significant. (J Respir Indo. 2020; 40(3): 144-9)Downloads
References
WHO, ed. Global Tuberculosis Report. Geneva, Switzerland, 2016.
WHO. Global strategy and targets for tuberculosis prevention, care and control [Online].2015 [Cited 2018 April 17]. Avalaible at : http://www.who.int/tb/post2015_TBstrategy.pdf?ua=1.
Pan SC, Ku CC, Kao D, Ezzati M, Fang CT, Lin HH. Effect of diabetes on tuberculosis control in 13 countries with high tuberculosis: a modeling study. Lancet Diabetes Endocrinol. 2015;3:323-30.
Ottmani S, Murray M, Jeon C, Baker M, Kapur A, Lönnroth K, et al. Consultation meeting on tuberculosis and diabetes mellitus : meeting summary and recommendations. Int J Tuberc Lung Dis. 2010;14:1513-7.
Restrepo B. Diabetes and tuberculosis. Microbiol Spectr. 2016;4:1-19.
Jeon C, Murray M. Diabetes mellitus increases the risk of active tuberculosis : a systematic review of 13 observational studies. Plos Med. 2008;5:1091-101.
IDF. IDF Diabetes Atlas 7th edition. 2015.
Wijaya I. Tuberkulosis paru pada penderita diabetes melitus. CDK. 2015;42:412-7.
Cahyadi A. Tuberkulosis paru pada pasien diabetes mellitus. J Indon Med Assoc. 2011;61:173-8.
Hwang H-G, Lee H-S, Choi J-S, Seo K-H, Kim Y-H, Na J-O. Risk factor influencing rebleeding after bronchial artery embolization on the management of hemoptysis associated with pulmonary tuberculosis. Tuberc Respir Dis. 2013;74:111-9.
Berkowitz N, Okorie A, Goliath R, Levitt N, Wilkinson RJ, Oni T. The prevalence and determinants of active tuberculosis among diabetes patients in Cape Town, South Africa, a high HIV/TB burden setting. Diabetes Res Clin Pract. 2018;138:16-25.
Kumpatla S, Sekar A, Achanta S. Characteristics of patients with diabetes screened for tuberculosis in a tertiary care hospital in South India. Public Health Action. 2013;3:23-8.
Lee MC, Lee CH, Shu C. The impact of diabetes mellitus and its control on the development of tuberculosis: a nationwide longitudinal study in Taiwan. Pharmacoepidemiol Drug Saf. 2016.
Wang J, Shen H. Review of cigarette smocking and tuberculosis in China: intervention is needed for smocking cessation among tuberculosis patients. BMC Public Health. 2009;9:292.
Jorgensen ME, Faurholt-Jepsen DI. s there an effect of glucose lowering treatment on incidence and prognosis of tuberculosis? A systematic review. Curr Diab Rep 2014;14:505.
Kumpatla S, Sekar A, Achanta S, al. e. Characteristics of patients with diabetes screened for tuberculosis in a tertiary care hospital in South India. Public Health Action 2013;3:23-8.
Brik A, Sale AM, Shoukry A, Shouman W. Surgery for hemoptysis in various pulmonary tuberculous lesions: a prospective study. Interactive CardioVascular and Thoracic Surgery. 2011;13:276-9.
Knott-Craig CJ, Oostuizen G, Rossouw G, Joubert JR, Barnard PM. Management and prognosis of massive hemoptysis: recent experience with 120 patients. J Thorac Cardiovasc Surg. 1993;105:394-7.
Restrepo BI, Fisher-Hoch SP, Crespo JG, Whitney E, Perez A, Smith B, et al. Type 2 diabetes and tuberculosis in a dynamic bi-national border population. Epidemiol Infect. 2007;135:483-91.
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